Why the study?
Does amiodarone reduce mortality in patients with heart failure?
Does amiodarone reduce mortality in patients with heart failure?
The safety and efficacy of amiodarone in reducing mortality in heart failure remains debated based on conflicting trial results.
Recent trials do not provide a definite answer H eart failure is a complex clinical syndrome that may lead to sudden cardiac death. Several trials have studied whether the antiarrhythmic agent amiodarone reduces such mortality in heart failure, 1 and two trials in particular have been at the centre of the debate: GESICA and CHF-STAT.
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Coceani et al. (2006) studied this question.
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