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January 1, 1970International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine

Microcolony Survival Assay for Cells of Mouse Intestinal Mucosa Exposed to Radiation

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Authors

HWH. Rodney WithersUniversity Hospitals Bristol NHS Foundation TrustMEM. M. ElkindTel Aviv University

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Implication

Microcolony technique measures survival of intestinal mucosa cells after radiation, indicating its sensitivity for small cell populations.

Key Points

  • The aim is to describe a microcolony method to assess the survival of clonogenic cells in mouse intestinal mucosa exposed to radiation.
  • Developed a microcolony technique for assaying cell survival.
  • Compared radiosensitivity measurements with a macrocolony method.
  • Applied the technique to whole-body radiation exposure.
  • Microcolony technique yielded radiosensitivity results consistent with those from the macrocolony method.
  • Demonstrated usefulness for assessing survival of small cell populations post-radiation.

Cite This Study

Withers et al. (1970) studied this question.

synapsesocial.com/papers/6a102015d8c5cf602efdb72bhttps://doi.org/10.1080/09553007014550291
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