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Myelofibrza je v porovnn s ostatnmi podjednotkami skupiny myeloproliferativnch onemocnn spojena s nejvy frekvenc doprovodnch konstitunch symptom a ptomnosti hepatosplenomegalie. K velmi astm pznakm myelofibrzy pat tak anmie rzn te, kter me bt pmm dsledkem patogenetickch mechanism myelofibrzy nebo nedoucm inkem samotn terapie JAK2 inhibitory. Oba typy anmi pinej nemocnm obdobn symptomy, nicmn pouze anmie spojen se samotnm zkladnm onemocnnm pedstavuje negativn prognostick faktor celkovho peit. Jednotliv JAK2 inhibitory se mezi sebou li svm vlivem na anmii.
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Natália Podstávková (2025) studied this question.
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