Why the study?
Current risk scores underestimate arrhythmic risk in arrhythmogenic cardiomyopathy patients with left ventricular involvement, as existing data in this population are contradictory and not exhaustive.
Current risk stratification scores underestimate arrhythmic risk in ACM patients with left ventricular involvement, highlighting a critical gap in identifying patients who need protection from arrhythmic death.
Answers are grounded in this paper and cite their sources.
May warrant cautious interpretation of current scores in left-involved ACM; leaves open development of validated stratification tools.
Arrhythmogenic cardiomyopathy (ACM) is a heart disease characterized by a fibrotic replacement of myocardial tissue and a consequent predisposition to ventricular arrhythmic events, especially in the young. Post-mortem studies and the subsequent diffusion of cardiac MRI have shown that left ventricular involvement in arrhythmogenic cardiomyopathy is common and often develops early. Regarding the arrhythmic risk stratification, the current scores underestimate the arrhythmic risk of patients with arrhythmogenic cardiomyopathy with left involvement. Indeed, the data on arrhythmic risk stratification in this group of patients are contradictory and not exhaustive, with the consequence of not correctly identifying patients at a high arrhythmic risk who deserve protection from arrhythmic death. We propose a literature review on arrhythmic risk stratification in patients with ACM and left involvement to identify the main features associated with an increased arrhythmic risk in this group of patients.
No takes yet. Share an insight, caveat, or question.
Varrenti et al. (2024) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: