What question did this study set out to answer?

To evaluate the impact of a 20-week endurance bicycle training program on plasma norepinephrine responses at rest, during absolute workloads, and during relative workloads.

October 1, 1981Journal of Applied Physiology

Plasma norepinephrine response to exercise before and after training in humans

View Full Paper

Ask AI

Bookmark

Why the study?

Does a 20-week exercise training program alter plasma norepinephrine response to exercise in healthy male subjects?

Population

10 healthy male subjects, mean age 37 +/- 2 years

Comparison

20-week training program on bicycle ergometer vs Before training (baseline evaluation)

Design

Cohort

Follow-up

20 weeks

Authors

FPFrançois PéronnetUniversity of British Columbia JCJean ClérouxJewish Rehabilitation Hospital HPHélène PerraultUniversity of Ottawa

Discussion

Member takes

Implication

May attenuate sympathetic response at absolute workloads; hypothesis-generating and leaves open effects on outcomes or broader populations.

Key Points

To evaluate the impact of a 20-week endurance bicycle training program on plasma norepinephrine responses at rest, during absolute workloads, and during relative workloads.
Assessed 10 healthy male volunteers (mean age 37 ± 2 years) before and after a 20-week cycle ergometer training regimen (three 30-minute sessions per week at 80% maximal heart rate).
Measured plasma norepinephrine levels at rest and during exercise using a radioenzymatic assay from antecubital venous blood samples.
Maximal oxygen uptake increased significantly post-training from 33 ± 2 to 42 ± 1 ml·kg⁻¹·min⁻¹, while resting plasma norepinephrine remained unchanged (167 ± 38 vs. 185 ± 29 pg·ml⁻¹).
At a matched absolute workload (735 ± 51 kg·m·min⁻¹), post-training plasma norepinephrine significantly decreased from 1,371 ± 286 to 687 ± 64 pg·ml⁻¹.
At identical relative workloads (heart rates of 158 ± 5 vs. 157 ± 5 beats·min⁻¹), plasma norepinephrine levels showed no significant change after training (1,371 ± 286 vs. 1,729 ± 371 pg·ml⁻¹).

Structured PICO

Does a 20-week exercise training program alter plasma norepinephrine response to exercise in healthy male subjects?

Population

10 healthy male subjects, mean age 37 +/- 2 years

Intervention

20-week training program on bicycle ergometer (three 30-min sessions per week at 80% of maximal heart rate)

Comparator

Before training (baseline evaluation)

Outcome

Plasma norepinephrine (NE) concentration at rest and during exercisesurrogate

Exercise training lowers the sympathetic nervous response (plasma norepinephrine) for a given absolute workload, but the response remains constant relative to maximal capacity.

Cite This Study

Péronnet et al. (1981) studied this question.

synapsesocial.com/papers/6a106a53e1a472cb5efcdb90 https://doi.org/10.1152/jappl.1981.51.4.812

View Full Paper

Ask AI

Bookmark

Implication

May attenuate sympathetic response at absolute workloads; hypothesis-generating and leaves open effects on outcomes or broader populations.

Plasma norepinephrine response to exercise before and after training in humans

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Plasma norepinephrine response to exercise before and after training in humans

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider