Mortality After Non–ST-Segment Elevation Myocardial Infarction

Figures

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  Figure 1. Participants Figure 1 illustrates the steps leading to the inclusion of 8,770 patients and 43,850 matched controls. CABG = coronary artery bypass grafting; CAG = coronary angiography; CAD = coronary artery disease; LVEF = left ventricular ejection fraction; MI = myocardial infarction; NSTEMI = non–ST-segment elevation myocardial infarction; PCI = percutaneous intervention; WDHR = Western Denmark Heart Registry.

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  Central Illustration. Impact of LVEF and CAD on Mortality Following NSTEMI Abbreviations as in Figures 1 and 2.

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  Figure 2. Cumulative 5-Year Mortality by LVEF and Extent of Obstructive CAD Figure 2 depicts the 5-year mortality grouped by LVEF, and obstructive CAD expressed as 1-3VD. An increase in risk is observed with decreasing LVEF and increasing extent of CAD, adding up to a risk difference of 37.1% between LVEF >50% and 1VD, and LVEF 10% to 40% and 3VD. VD = vessel disease; other abbreviations as in Figure 1.

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  Figure 3. Spline Regression Analysis of LVEF and Mortality Risk Figure 3 depicts a spline regression analysis of the 5-year mortality risk by reported LVEF. The median LVEF of 55% is set as a reference, and the darker areas represent 95% CI. The HR was adjusted for sex, age, hypertension, previous ischemic stroke, peripheral artery disease, CAD, atrial fibrillation, smoking, and diabetes. Abbreviations as in Figure 1.

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  Figure 4. Mortality During Follow-Up Grouped by LVEF and Obstructive CAD Figure 4 depicts the 5-year cumulated mortality risk and risk tables: (A) grouped by LVEF, with the risk reaching almost 40% for patients with the lowest LVEF, and (B) grouped by the extent of CAD expressed as 1VD, 2VD, and 3VD, with the risk reaching more than 30% for 3VD. Abbreviations as in Figures 1 and 2.