In 1890 Browicz described an intracellular vibratory movement in human erythrocytes, which he believed to be a pathological condition, from four cases of anaemia. It was found in one case of pernicious anaemia, and was stated to disappear following a remission; it was also found in two cases of malignant disease. He ascribed it to abnormal reactions between pathological erythro- cytes and their plasma. In his view it was not a vital phenomenon since it persisted at room temperature when leucocytic activity had subsided, and he stated that it continued for at least 24 hours. Cabot (1901) made several references to this motion. He stated:
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R. J. V. Pulvertaft (1949) studied this question.