This review highlights the interplay between physical activity, atherosclerosis-driven inflammation, and the microbiome in cardiovascular health.
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Interplay of activity, inflammation, and microbiome in CVD is hypothesis-generating; prospective trials needed before clinical adoption.
Cardiovascular health is a primary research focus, as it is a leading contributor to mortality and morbidity worldwide, and is prohibitively costly for healthcare. Atherosclerosis, the main driver of cardiovascular disease, is now recognized as an inflammatory disorder. Physical activity (PA) may have a more important role in cardiovascular health than previously expected. This review overviews the contribution of PA to cardiovascular health, the inflammatory role of atherosclerosis, and the emerging evidence of the microbiome as a regulator of inflammation.
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Fernandez et al. (2018) studied this question.
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