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A T OCCUR in abnormally T high concentration in the sera ot multiple inyeloma patients are characterized by their electrophoretic homogeneity. The electrophoretic mobility of the multiple myeloma proteins varies in different individualsle and they are classified as gamma-, beta-, and alphaglobulins. The MM globulins though antigenically closely related to normal gamma-globulin4. 19 were found to be deficient i n some antigenslo. 1 1 , 1 2 , 1 7 or to contain antigens absent in normal gamma-globulinll. 1 2 9 1 7 or human plasma.1l. 12.18 (The abbreviation MM will be used to designate multiple myeloma. The mobilities of the MM globulins are given as cm.2 per sec. per v . X ~O -~. )
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Korngold et al. (1956) studied this question.
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