Why the study?
Treatment decisions for symptomatic and asymptomatic patients are routinely based on trials from over 30 years ago, leaving controversies in measuring stenosis and managing carotid stenosis for stroke prevention.
Design
Review article
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Individualized assessment remains essential amid carotid stenosis uncertainties; leaves open critical gaps for targeted research.
The carotid artery is unique; it is the only vessel to bifurcate into a bulb larger than itself. The history of its anatomic description, understanding of its pathophysiology and evolution of its imaging are relevant to current controversies regarding measurement of stenosis, surgical/endovascular therapies and medical management of carotid stenosis in stroke prevention. Treatment decisions on millions of symptomatic and asymptomatic patients are routinely based on information from clinical trials from over 30 years ago. This article briefly summarizes the highlights of past research in key areas and discuss how they led to current challenges of diagnosis and treatment.
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Pelz et al. (2024) studied this question.
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