Treatment outcomes among young persons living with HIV who transitioned to adult care in southern Nigeria: A retrospective cohort study

Esther Nwanja; Uduak Akpan; Otoyo Toyo; Ogheneuzuazo Onwah; Chinazom N. Ekwueme; Ofonime Dixon-Umo; Bala Gana; Godson Ndubueze; Ijeoma Uchenna Itanyi; Echezona E. Ezeanolue; Augustine Idemudia; Onyeka Igboelina; Dolapo Ogundehin; Ezekiel James; Chika Obiora‐Okafo; Olugbenga Asaolu; Bayo Onimode; Moses Katbi; Jemeh Pius; Omosalewa Oyelaran; Okezie Onyedinachi; Adeoye Adegboye; Andy Eyo

doi:10.1371/journal.pone.0321962

Key Points

To compare 12- and 24-month treatment retention and viral suppression among young persons living with HIV who transitioned to adult care before versus after implementing a peer-based transition preparedness model.
Conducted a retrospective cohort study across 155 primary, secondary, and tertiary healthcare facilities in southern Nigeria.
Extracted medical records of 1,555 young persons living with HIV who transitioned to adult care at age 25 in 2018 (pre-model, n = 343) and 2021 (post-model, n = 1,212).
Applied logistic regression analysis to compare client continuity on treatment and undetectable viral load between cohorts at 12 and 24 months post-transition.
Continuity on treatment was significantly higher in the 2021 cohort than in the 2018 cohort at 12 months (96.7% vs 80.2%, p < 0.001) and at 24 months (92.7% vs 77.6%, p < 0.001).
Undetectable viral load rates were significantly greater in the 2021 cohort compared with the 2018 cohort at 12 months (96.1% vs 60.1%, p < 0.001) and at 24 months (93.3% vs 80.6%, p < 0.001).

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Implication

Retrospective cohort study demonstrates improved treatment retention and viral suppression in young persons transitioning to adult HIV care, highlighting the benefit of peer-based preparation.

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Cite This Study

Nwanja et al. (2025) studied this question.

synapsesocial.com/papers/6a107a5a8090e499da613b6b https://doi.org/10.1371/journal.pone.0321962

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Treatment outcomes among young persons living with HIV who transitioned to adult care in southern Nigeria: A retrospective cohort study

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Treatment outcomes among young persons living with HIV who transitioned to adult care in southern Nigeria: A retrospective cohort study

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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