Cycle exercise in women with well-controlled isolated systolic hypertension caused significantly higher systolic blood pressure compared to normotensive controls (194 vs 153 mm Hg; P<0.001).
Observational (n=38)
Do older women with controlled isolated systolic hypertension have exaggerated blood pressure responses to exercise compared to normotensive controls?
Older women with medically controlled isolated systolic hypertension exhibit exaggerated systolic blood pressure responses to both dynamic and static exercise, indicating potential cardiovascular risk during physical exertion.
Absolute Event Rate: 194% vs 153%
p-value: p=<0.001
INTRODUCTION: Exercise is generally regarded as beneficial for health, but the consequent increases in blood pressure might pose a risk for hypertensive subjects. The purpose of this study was to determine blood pressure responses to dynamic exercise and sustained handgrip in patients with isolated systolic hypertension (ISH) who were stable on medication. METHODS: Nineteen female ISH patients (66 ± 5 yr) and 19 age-matched normotensive (NT) female controls undertook a 5-min cycle exercise (60% heart rate reserve HRR) and a 2-min handgrip exercise (30% maximum voluntary contraction). Blood pressure responses were measured using an oscillometric cuff, together with heart rate and resting brachial pulse transit times. RESULTS: Systolic blood pressure (SBP) levels after cycle exercise were 194 ± 18 and 153 ± 19 mm Hg for ISH and NT, respectively, with the increase above resting being greater for ISH (P < 0.001), and only small changes were found in diastolic blood pressure (DBP). During handgrip exercise, SBP rose to 168 ± 19 and 140 ± 8 mm Hg for ISH and NT, respectively. The increases above baseline were greater for ISH both during the exercise and postexercise circulatory occlusion (P = 0.017). The increase in DBP levels during exercise and postexercise occlusion were similar in ISH and NT, suggesting little difference in metaboreflex sensitivity. Pulse transit time was shorter for ISH compared with NT (166 ± 6 ms and 242 ± 24 ms, respectively, P < 0.001), indicating stiffer arteries, which would increase SBP but not DBP. CONCLUSION: Despite being well controlled and normotensive control subjects at rest, ISH patients had high SBP responses to both dynamic and static exercises, which may constitute a risk for cardiovascular incidents.
Ubolsakka‐Jones et al. (Sun,) conducted a observational in Isolated systolic hypertension (n=38). Dynamic exercise and sustained handgrip vs. Normotensive controls was evaluated on Systolic blood pressure response to cycle exercise (p=<0.001). Cycle exercise in women with well-controlled isolated systolic hypertension caused significantly higher systolic blood pressure compared to normotensive controls (194 vs 153 mm Hg; P<0.001).
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