Why the study?
Does the metaboreflex contribute to the increase in muscle sympathetic nerve activity to contracting muscle during static exercise in humans?
Does the metaboreflex contribute to the increase in muscle sympathetic nerve activity to contracting muscle during static exercise in humans?
Central command, rather than the metaboreflex, is the primary mechanism responsible for increasing muscle sympathetic nerve activity to contracting muscle during sustained static exercise.
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Central command, not metaboreflex, drives early MSNA rise in contracting muscle; challenges prior models and leaves mechanisms in disease open.
Boulton et al. (2018) studied this question.
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