Key result
NSTE-ACS in-hospital mortality shows no change from 2015 to 2017 despite rising disease morbidity.
Why the study?
NSTE-ACS is a common cause of hospital admissions among coronary artery disease patients, motivating an assessment of clinical and epidemiological patterns and hospital outcomes in clinical practice.
Observational (n=4,884)
Yes
Absolute Event Rate: 3.21% vs 3.74%
p-value: p=0.681
Between 2015 and 2017 in Kemerovo, NSTE-ACS morbidity increased while in-hospital mortality remained relatively high at ~3.36% despite a 33% rate of invasive treatment.
Stable mortality despite rising NSTE-ACS incidence should not yet change practice; leaves open whether higher invasive rates improve outcomes.
Background. Non-ST elevation acute coronary syndrome (NSTE-ACS) is a common cause of hospital admissions of coronary artery disease patients. Aim. To assess clinical and epidemiological patterns and hospital outcomes of treatment of NSTE-ACS in Kemerovo in period from 2015 to 2017. Methods. 4884 patients with NSTE-ACS admitted to the Kemerovo healthcare facilities in the period from 2015 to 2017 were included in a retrospective observational study. In-hospital period was subjected to the analysis. Results. The morbidity of NSTE-ACS increased by 16.92% (from 267.78 cases in 2015 to 302.13 cases per 100 thousand population in 2017). The rate of invasive treatment strategies in patients with NSTE-ACS did not change significantly within the study period (about 33%). In-hospital mortality from NSTE-ACS slightly decreased (from 3.74% in 2015 to 3.21% in 2017, p = 0.681). Conclusion. The observational study reported a tendency towards increasing prevalence of NSTE-ACS in a large industrial center within the 3-year period by 16.92%. Nevertheless, the availability of invasive treatment in Kemerovo within the study period remained high (33%). However, relatively high in-hospital mortality rate (3.36%) in NSTEMI has been determined and requires additional studies.
No takes yet. Share an insight, caveat, or question.
Синьков et al. (2019) conducted an observational in Non-ST elevation acute coronary syndrome (NSTE-ACS) (n=4,884). Standard clinical practice was evaluated on In-hospital mortality (p=0.681). In-hospital mortality for patients with NSTE-ACS did not significantly change between 2015 and 2017 (3.74% vs 3.21%, p=0.681), despite a 16.92% increase in disease morbidity.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: