Key result
Exercise training in conscious dogs reduced heart rate during a submaximal test by an average of 20 beats/min and increased the maximum derivative of left ventricular pressure by 2,200 Torr/s.
Why the study?
Does exercise training improve cardiac function in conscious dogs?
Population
21 mongrel dogs instrumented to measure ascending aortic flow, left ventricular pressure, and left atrial…
Comparison
Exercise training program alternating daily… vs Untrained animals / untrained state
Design
Preclinical
Authors
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Cardiac adaptations seen in dogs warrant mechanistic study; leaves open translation to human exercise interventions.
Does exercise training improve cardiac function in conscious dogs?
Exercise training in conscious dogs leads to reflex adaptations of the nervous system that improve cardiac function, evidenced by reduced heart rate and increased left ventricular pressure derivative during submaximal exercise.
H. L. Stone (1977) studied this question. Exercise training vs. Untrained animals was evaluated on Heart rate and maximum derivative of left ventricular pressure during standardized submaximal test. Exercise training in conscious dogs reduced heart rate during a submaximal test by an average of 20 beats/min and increased the maximum derivative of left ventricular pressure by 2,200 Torr/s.