Key result
Long-slow home hemodialysis produced superior blood pressure control compared to short in-center hemodialysis, with lower pre- and postdialysis systolic and ambulatory blood pressures.
Why the study?
Does long-slow home hemodialysis improve blood pressure control compared to standard in-center hemodialysis in home hemodialysis patients?
Population
9 home hemodialysis patients, not on antihypertensive drugs
Comparison
Long-slow hemodialysis at home for 6-8 hours, 3… vs Standard hemodialysis in the dialysis center for…
Design
RCT, Randomized sequence (crossover)
Follow-up
8 weeks per phase
Authors
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Supports long-slow home hemodialysis for BP optimization in dialysis patients; extends RCT evidence on extended-duration regimens.
RCT (n=9)
Crossover
Does long-slow home hemodialysis improve blood pressure control compared to standard in-center hemodialysis in home hemodialysis patients?
Long-slow home hemodialysis provides superior blood pressure control compared to standard in-center hemodialysis, independent of extracellular fluid volume changes.
McGregor et al. (2001) conducted an RCT in End-stage renal disease requiring hemodialysis (n=9). Long-slow home hemodialysis vs. Short in-center hemodialysis (3.5-4.5 hours, 3 times weekly) was evaluated on Blood pressure control. Long-slow home hemodialysis produced superior blood pressure control compared to short in-center hemodialysis, with lower pre- and postdialysis systolic and ambulatory blood pressures.
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