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April 1, 1991The Journal of Experimental MedicineOpen Access

A recombinant human receptor antagonist to interleukin 1 improves survival after lethal endotoxemia in mice.

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Authors

HAH. Richard AlexanderRutgers, The State University of New JerseyGDGerard M. DohertyBrigham and Women's HospitalCBC M BureshNational Institutes of Health

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Alexander et al. (1991) studied this question.

synapsesocial.com/papers/6a109b2ad478ddac0ffd442chttps://doi.org/10.1084/jem.173.4.1029
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Also Consider

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  1. 1In vivo inflammatory activity of epidermal cell-derived thymocyte activating factor and recombinant interleukin 1 in the mouse.1986 · 130 citations
  2. 2Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition.1988 · 988 citations
  3. 3Passive immunization against tumor necrosis factor partially abrogates interleukin 2 toxicity.1989 · 84 citations