Effect of Statins on Risk of Coronary Disease: A Meta-analysis of Randomized Controlled Trials

Key Points

• To evaluate the effect of statins on the risk of coronary disease through a meta-analysis of existing data.
• Conducted a meta-analysis of randomized controlled trials
• Included trials assessing the impact of statins on coronary disease
• Analyzed outcomes related to cholesterol levels and cardiovascular events.
• Statin use significantly reduced the risk of coronary disease by 25% (RR 0.75, 95% CI 0.66-0.86, p<0.001).
• Cholesterol levels decreased significantly among statin users, correlating with reduced coronary event rates.