Key result
HCM is associated with a ~3-fold higher frequency of presystolic A waves compared to athletes.
Why the study?
Differentiating hypertrophic cardiomyopathy from athlete's heart by echocardiography can be difficult in clinical practice, prompting evaluation of presystolic A wave on Doppler echocardiography.
Does the presence of presystolic A wave (PSAW) assessed by Doppler echocardiography differentiate between non-obstructive hypertrophic cardiomyopathy and athlete's heart?
Observational (n=52)
Does the presence of presystolic A wave (PSAW) assessed by Doppler echocardiography differentiate between non-obstructive hypertrophic cardiomyopathy and athlete's heart?
Absolute Event Rate: 44% vs 16%
p-value: p=0.026
The presence of a presystolic A wave on Doppler echocardiography may serve as a useful parameter to differentiate hypertrophic cardiomyopathy from athlete's heart.
Background: Even though hypertrophic cardiomyopathy (HCM) can be distinguished from the athlete’s heart with a difference in echocardiographic measurements, difficulties may be encountered in clinical practice from time to time. The aim of this study was to evaluate the use of presystolic A wave (PSAW) assessed by the Doppler echocardiography for differentiating between HCM and athlete’s heart. Methods: A total of 52 subjects were included in the present study, of which, 27 had HCM and 25 were athletes. The pulsed Doppler assessment of the left ventricular outflow tract was performed on the ventricular face from the immediate proximal of the aortic valve on the apical five-chamber view. Allpatients were assessed for the presence of PSAW,and the velocity of this wave was recordedin PSAW positive subjects. Results: The frequency of PSAW was found to be higher in patients with HCM [n = 12 (44%)] than in athletes [n = 4 (16%)] (p = 0.026). PSAW velocity measurements were observed to be higher in the HCM group; however, there was no statistical significance [53 ms (36–84)], [68 ms (35–193)], (p = 0.362). Conclusion: While there is a need for scaling-up similar studies, the current findings suggest that PSAW can be used as a distinguishing parameter for differentiating HCM and athlete’s heart.
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Kırcı et al. (2020) conducted an observational in Non-obstructive Hypertrophic Cardiomyopathy and Athlete's Heart (n=52). Hypertrophic cardiomyopathy vs. Athlete's heart was evaluated on Frequency of presystolic A wave (PSAW) (p=0.026). The frequency of presystolic A wave was significantly higher in patients with hypertrophic cardiomyopathy (44%) compared to athletes (16%, p=0.026).
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