Why the study?
Are there gender differences in the management, treatment benefit, and outcomes of acute coronary syndromes?
Are there gender differences in the management, treatment benefit, and outcomes of acute coronary syndromes?
Reported gender differences in ACS management and outcomes remain inconsistent, largely due to variations in statistical adjustment for baseline characteristics.
ACS management should remain gender-neutral pending clearer data; leaves open whether adjustment methods explain prior inconsistencies.
Acute Coronary Syndromes are the most frequent manifestations of coronary heart disease (CHD). Gender differences in treatment intensity, including differences in level of care, have been reported. Also differences in benefit from certain treatments, especially invasive treatment, have been discussed. Finally, differences in outcome between men and women have been proposed. Results have been inconsistent, partly depending on if and how adjustment for differences in background characteristics has been made.
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Alfredsson et al. (2010) studied this question.
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