Key result
Women with non-ST-segment elevation acute coronary syndromes were independently associated with lower in-hospital indication of coronary angiography compared to men (OR 0.73; 95% CI 0.65-0.82).
Why the study?
Are there gender differences in the treatment of patients with acute coronary syndromes?
Observational
Are there gender differences in the treatment of patients with acute coronary syndromes?
Women with acute coronary syndromes receive more conservative treatment strategies and fewer secondary prevention medications compared to men, highlighting a significant gender bias in care.
mtsAc, 1 , hernan dov Al mtsAc,1 Results In patients with non ST-segment elevation acute coronary syndromes, women were independently associated with lower in-hospital indication of coronary angiography (OR 0.73, 95% CI 0.65 to 0.82), and lower use of IIb/IIIa inhibitors than men. After adjusted analyses, there were no significant differences between men and women in the use of reperfusion therapy for myocardial infarction or in in-hospital mortality. At discharge, women were significantly less likely than men to receive prescriptions for beta-blockers and statins, and more likely to receive prescriptions for benzodiaz- epines. Conclusions These findings suggest gender bias in the treatment of patients with acute coronary syndromes, evidenced by selection of a more conservative strategy and lower pre- scription of drugs recommended for secondary prevention in women. Differences be- tween genders in the approach of acute coronary syndromes should be studied more deeply, as the underutilization of evidence-based therapies could have an impact on women's clinical outcomes.
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Mariani et al. (2013) conducted an observational in Acute Coronary Syndromes. Female gender vs. Male gender was evaluated on In-hospital indication of coronary angiography (OR 0.73, 95% CI 0.65-0.82). Women with non-ST-segment elevation acute coronary syndromes were independently associated with lower in-hospital indication of coronary angiography compared to men (OR 0.73; 95% CI 0.65-0.82).
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