Key result
Electrical activity from motor neurones dictates muscle contractile properties, where high amounts of activity induce a slow phenotype and low amounts induce a fast phenotype.
Design
Review
Authors
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Informs activity-based muscle rehabilitation strategies; leaves open neurotrophic substance roles.
The pattern of electrical activity from motor neurones is the primary driver of muscle contractile phenotype, while the role of neurotrophic substances remains unclear.
Kristian Gundersen (1998) conducted a review in Muscle contractile properties. Electrical activity was evaluated. Electrical activity from motor neurones dictates muscle contractile properties, where high amounts of activity induce a slow phenotype and low amounts induce a fast phenotype.
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