Key Points
- To review established and evolving risk stratification algorithms that guide decision-making between percutaneous coronary intervention and coronary artery bypass grafting in complex coronary artery disease.
- Literature-based narrative evaluation of anatomical, clinical, and combined risk-scoring models.
- Assessment of emerging strategies incorporating functional anatomy, revascularisation completeness, and patient-centered risk-benefit trade-offs.
- Purely anatomical scores, such as the original SYNTAX score, are limited by their exclusion of clinical patient variables.
- Combining clinical characteristics with anatomical scores enhances risk prediction and supports multidisciplinary heart team revascularisation choices.
- Novel algorithms increasingly target functional anatomy and individualized benefit-risk balances between stenting and surgical revascularisation.
Structured PICO
PPopulationPatients electing to undergo percutaneous coronary intervention (PCI) or with complex coronary artery disease
IInterventionRisk scoring algorithms (e.g., SYNTAX score, clinical and anatomical models)
This review highlights the evolution of risk scoring algorithms for PCI, emphasizing the integration of clinical and anatomical variables to personalize revascularization choices.