What question did this study set out to answer?

To assess the validity of an antenatal-clinic-based sentinel surveillance system in estimating HIV-1 prevalence and long-term epidemic trends compared with general population cross-sectional surveys.

April 1, 2000JAIDS Journal of Acquired Immune Deficiency Syndromes

Monitoring of HIV-1 Infection Prevalence and Trends in the General Population Using Pregnant Women as a Sentinel Population: 9 Years Experience From the Kagera Region of Tanzania

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To assess the validity of an antenatal-clinic-based sentinel surveillance system in estimating HIV-1 prevalence and long-term epidemic trends compared with general population cross-sectional surveys.
Conducted serial cross-sectional surveys using multistage cluster sampling in the general population (1987, 1993, 1996) alongside sentinel surveillance of consecutive, first-visit pregnant women attending antenatal care (1990, 1993, 1996) in Bukoba, Tanzania.
Assessed HIV-1 infection status using two independent enzyme-linked immunosorbent assays (ELISA), employing unlinked anonymous testing for sentinel participants.
Age-adjusted HIV prevalence among antenatal care attendees decreased from 22.4% (95% CI, 20.6–25.2) in 1990 to 16.1% (95% CI, 15.9–18.8) in 1993 and 13.7% (95% CI, 11.8–14.3) in 1996.
Age-adjusted HIV prevalence among adult women in the general population catchment area decreased from 29.1% (95% CI, 24.4–34.6) in 1987 to 18.7% (95% CI, 15.1–23.0) in 1993 and 14.9% (95% CI, 12.0–17.1) in 1996.

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Implication

Surveillance study demonstrates matching HIV-1 declines in antenatal clinics and the community, indicating pregnant women reliably reflect general population epidemic trends.

Cite This Study

Kwesigabo et al. (2000) studied this question.

synapsesocial.com/papers/6a10c5a0f85e2d3f759f5e41 https://doi.org/10.1097/00126334-200004150-00008

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Implication

Surveillance study demonstrates matching HIV-1 declines in antenatal clinics and the community, indicating pregnant women reliably reflect general population epidemic trends.

Monitoring of HIV-1 Infection Prevalence and Trends in the General Population Using Pregnant Women as a Sentinel Population: 9 Years Experience From the Kagera Region of Tanzania

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Discussion

Implication

Cite This Study

Monitoring of HIV-1 Infection Prevalence and Trends in the General Population Using Pregnant Women as a Sentinel Population: 9 Years Experience From the Kagera Region of Tanzania

Key Points

Discussion

Implication

Cite This Study

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