Key result
Review details propensity score matching and inverse probability weighting to address confounding in OAC research.
Why the study?
Comparative effectiveness research using real-world data faces confounding by indication due to lack of randomization, prompting the need to elevate understanding of propensity score matching and inverse probability of treatment weighting in atrial fibrillation.
Comparison
Propensity score matching vs inverse probability of treatment weighting
Design
Review
Authors
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Does not support changing OAC prescribing in AF from observational data; leaves open whether PSM and IPTW refine CER estimates.
This review provides a methodological overview of propensity score matching and inverse probability of treatment weighting for comparative effectiveness research of oral anticoagulants in atrial fibrillation.
Allan et al. (2020) conducted a review in Atrial fibrillation. Propensity score matching and inverse probability of treatment weighting was evaluated. This review describes the fundamentals of propensity score matching and inverse probability of treatment weighting to address confounding by indication in comparative effectiveness research of OACs.
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