Why the study?
The study aimed to illustrate the feasibility, safety, and outcomes of catheter ablation using the novel KODEX-EPD dielectric three-dimensional mapping system.
Is catheter ablation using the KODEX-EPD system safe and effective in patients with supraventricular arrhythmias?
Observational (n=272)
Yes
Is catheter ablation using the KODEX-EPD system safe and effective in patients with supraventricular arrhythmias?
Catheter ablation of supraventricular arrhythmias using the novel KODEX-EPD dielectric mapping system is feasible, safe, and achieves high immediate success rates.
Answers are grounded in this paper and cite their sources.
Observational data suggest KODEX-EPD ablation is feasible with high acute success; leaves open need for randomized confirmation of durability and safety.
BACKGROUND: The KODEX-EPD system is a novel, dielectric three-dimensional mapping system. We aim to illustrate the feasibility, safety, and outcomes of ablation using the KODEX-EPD system. METHODS: A total of 272 patients with supraventricular arrhythmias were enrolled and underwent catheter ablation using the KODEX-EPD system from October 2020 to July 2021. The feasibility, safety, and ablation outcomes were analyzed. RESULTS: Of the enrolled patients, 15 (5.4%) had atrial tachycardia (AT), 88 (31.4%) had atrioventricular reentrant tachycardia (AVRT), 141 (50.4%) had atrioventricular nodal reentrant tachycardia (AVNRT), 34 (12.1%) had atrial fibrillation (AF), and 9 (3.2%) had atrial flutter (AFL). All AF patients included were first-do-pulmonary vein isolation (PVI); there were 26 paroxysmal AF and 8 persistent AF. All patients achieved immediate success of ablation. The mean follow-up duration was 11.8 ± 2.4 months. One patient (1.1%) in the AVRT subgroup and two patients (1.4%) in the AVNRT subgroup experienced recurrence. When considering a three-month blanking time, the estimated freedom of AF at one-year post-ablation with and without AADs was 75.7% and 70.4%, respectively. The Kaplan-Meier analysis showed no significant difference in the overall AF recurrence (log-rank; P = 0.931) or AAD-free AF recurrence (log-rank; P = 0.841) between RFCA and cryoablation. One patient had mild pulmonary embolism. None of the patients died or had a cerebrovascular event in the periprocedural period. CONCLUSIONS: This retrospective, two-center study demonstrated that catheter ablation of supraventricular arrhythmias using the KODEX-EPD system is feasible, safe, and effective. Trial registration Retrospectively registered.
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Ding et al. (2022) conducted an observational in Supraventricular arrhythmias (n=272). Catheter ablation using the KODEX-EPD system was evaluated on Immediate success of ablation.
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