Key result
Single RF ablation efficacy for AF remains stable at 12 months.
Why the study?
The study was conducted to analyze temporal trends in patient data and procedural efficacy during 12-month follow-up among patients undergoing a single radiofrequency catheter ablation for atrial fibrillation.
Does the efficacy of a single radiofrequency ablation procedure for atrial fibrillation change over time as patient characteristics evolve?
Observational (n=585)
No
Does the efficacy of a single radiofrequency ablation procedure for atrial fibrillation change over time as patient characteristics evolve?
Despite an increasing proportion of patients with persistent AF, chronic heart failure, and larger left atria undergoing more extensive ablation, the 12-month efficacy of a single RF ablation procedure remained stable over a 6-year period.
Answers are grounded in this paper and cite their sources.
RF ablation efficacy for AF remained stable despite rising patient complexity; supports real-world durability in observational cohorts but leaves open causal confirmation.
Background and Objectives: Atrial fibrillation (AF) is the most common supraventricular arrhythmia. Currently, catheter ablation is a preferred treatment strategy. The main objective of our study was a temporary trends analysis of patients’ data undergoing a single AF ablation procedure using radiofrequency energy (RF). The efficacy of the procedure underwent assessment during a 12-month follow-up. Materials and Methods: We analyzed 585 consecutive patients with symptomatic, recurrent, and drug-refractory AF hospitalized in our department between 2013 and 2018 who underwent RF ablation supported by a 3D electroanatomical system. The baseline characteristics, periprocedural parameters, and efficacy of the procedure at 6-, 9- and 12-month follow-ups were analyzed over the years. Results: The number of patients undergoing ablation increased. Patients with paroxysmal AF predominated (71.5%). However, the number of patients with the persistent type of arrhythmia increased over the years. The percentage of patients with chronic heart failure (CHF) increased to 27.5% in 2018, and patients presented with increasingly larger left atria (LA). In all patients, circumferential pulmonary vein isolation was performed. The percentage of patients who underwent arrhythmogenic substrate modification and cavotricuspid isthmus ablation increased. Over the years, the efficacy of a single procedure at the 12-month follow-up remained without significant differences between the years (72.0%, 69.6%, 75.5%, 74.8%, 71.7%, 71.7%). Conclusions: The rate of patients with CHF and advanced LA disease undergoing more extensive ablation increased over the years. The efficacy of a single procedure remained without significant differences between the years.
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Myrda et al. (2022) conducted an observational in Atrial fibrillation (n=585). Radiofrequency ablation supported by a 3D electroanatomical system was evaluated on Efficacy of a single procedure at 12-month follow-up. The efficacy of a single radiofrequency ablation procedure for atrial fibrillation remained stable between 2013 and 2018 (ranging from 69.6% to 75.5% at 12 months).
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