Key result
Thoracoscopic epicardial ablation maintains ~56% freedom from atrial arrhythmia recurrence at 3-year follow-up.
Why the study?
Left atrial epicardial ablation has evolved as a rhythm control strategy for symptomatic drug-refractory AF or high risk of catheter ablation failure, but its safety and efficacy require evaluation.
Cohort (n=81)
No
May support thoracoscopic epicardial ablation for AF rhythm control; hypothesis-generating and leaves open need for RCTs.
AIMS: Atrial fibrillation (AF) is associated with reduced quality of life and increased risk of ischaemic cerebrovascular events. The left atrial epicardial ablation procedures have evolved towards a successful and safe rhythm control strategy for patients with symptomatic drug-refractory paroxysmal, persistent or post-ablation AF or with a high risk of catheter ablation failure. The aim was to evaluate the efficacy and safety of thoracoscopic ablation at our instituiton. METHODS: We observed 81 patients undergoing thoracoscopic ablation from January 2015 to December 2019. RESULTS: The mean age was 61.3±8.5 years and the average duration of AF was 3.1±2.6 years. The cohort consisted of 16.5% of paroxysmal AF, 36.7% persistent, and 46.8% of long-standing AF. The procedure was completed in 79 patients; during follow-up, 15 patients (19%) received radiofrequency ablation. Freedom from atrial arrhythmia recurrence was 55.7% after a follow-up (FUP) period of 3.1±1.4 years. At the follow-up visit, sinus rhythm was present in 81% of patients. No relationships between arrhythmia recurrence and BMI, LVEF, left atrial dimension, gender, and AF duration were found. Major complications were noticed in 4 patients (5.0%); 2 had peripheral embolisation, 2 patients were converted to a sternotomy. At the time of the FUP visit, 25.3% of patients were using antiarrhythmic and 74.7% were still using anticoagulants. CONCLUSION: In the majority of patients, sinus rhythm remained despite a considerable atrial tachycardia recurrence rate, with a relatively low percentage of patients on antiarrythmic drugs.
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Troubil et al. (2022) conducted a cohort in Atrial fibrillation (n=81). Thoracoscopic epicardial ablation was evaluated on Freedom from atrial arrhythmia recurrence. Thoracoscopic epicardial ablation resulted in a 55.7% freedom from atrial arrhythmia recurrence after a mean follow-up of 3.1 years, with 81% of patients remaining in sinus rhythm.
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