Accessory atrioventricular pathways may be a contributing factor to sudden death in patients with hypertrophic cardiomyopathy.
May warrant accessory pathway evaluation in HCM sudden death risk assessment; hypothesis-generating and requires prospective validation before practice change.
Sudden death is a known but unpredictable complication of hypertrophic cardiomyopathy. We describe two patients who both had a strong family history of the disorder complicated by sudden death. Necropsy disclosed accessory bypass tracts, concealed in one and previously suspected in the other. One died from ventricular fibrillation and the other, who died outside hospital, had previously complained of palpitation. Arrhythmia complicating pre-excitation appears to be one of the factors responsible for sudden death in hypertrophic cardiomyopathy.
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Krikler et al. (1980) studied this question.
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