Key result
Higher vegetable nitrate intake was associated with a 17% lower risk of ischemic cerebrovascular disease events per 29 mg/d increase (P=0.02) and lower CCA-IMT in elderly women.
Why the study?
Does higher vegetable nitrate intake reduce carotid atherosclerosis and ischemic cerebrovascular disease events in elderly women?
Population
1,226 elderly women
Comparison
Higher vegetable-derived nitrate intake vs Lower vegetable-derived nitrate intake
Design
Cohort
Follow-up
14.5 years
Authors
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Should not change practice; leaves open whether vegetable nitrate causally reduces cerebrovascular risk in elderly women.
Cohort (n=1,226)
Does higher vegetable nitrate intake reduce carotid atherosclerosis and ischemic cerebrovascular disease events in elderly women?
Effect estimate: 17% lower risk
p-value: p=0.02
Higher dietary intake of vegetable nitrate is associated with reduced carotid intima-media thickness and a lower long-term risk of ischemic cerebrovascular events in older women.
Bondonno et al. (2017) conducted a cohort in carotid atherosclerosis and ischemic cerebrovascular disease (n=1,226). Vegetable nitrate intake was evaluated on ischemic cerebrovascular disease events (17% lower risk, p=0.02). Higher vegetable nitrate intake was associated with a 17% lower risk of ischemic cerebrovascular disease events per 29 mg/d increase (P=0.02) and lower CCA-IMT in elderly women.
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