C-kit mutations in core binding factor leukemias

To the editor: C-kit mutations in core binding factor leukemias Positivity for CD117(c-kit) expression is present in 80% of acute myeloblastic leukemia (AML) cases,[1][1] and has been associated with the expression of CD33, a marker of myeloid precursors, and CD13, a myeloid-associated antigen.[2