Key result
Minimally invasive AVR with MiECC linked to ~1.8 fewer ICU days and less hemorrhage versus sternotomy.
Why the study?
Critics sustain that potential advantages of minimally invasive aortic valve surgery are offset by longer cross-clamp and cardiopulmonary bypass durations that may impair clinical outcomes.
Does minimally invasive aortic valve replacement on minimally invasive extracorporeal circulation improve perioperative outcomes in high-risk patients undergoing aortic valve surgery?
Cohort (n=200)
No
Does minimally invasive aortic valve replacement on minimally invasive extracorporeal circulation improve perioperative outcomes in high-risk patients undergoing aortic valve surgery?
Absolute Event Rate: 1% vs 2.8%
p-value: p=0.04
A multidisciplinary approach combining minimally invasive aortic valve replacement with minimally invasive extracorporeal circulation improves perioperative recovery and clinical outcomes compared to conventional techniques in high-risk patients.
We present our multidisciplinary and multistep strategy in patients undergoing minimally invasive aortic valve replacement (mAVR) on minimally invasive extracorporeal circulation (MiECC) compared with control groups of a single strategy and conventional techniques. This cohort study included high-risk patients (Society of Thoracic Surgeons [STS] risk score >8%) undergoing aortic valve surgery under different strategies during the period from January 2017 until March 2019. Patients were matched for age, gender, body mass index, and STS score: group 1 (MiAVR) based on a minimally invasive technique with J-mini-sternotomy, rapid deployment valve (RDV), and type IV customized MiECC; group 2 (control-mAVR) consisted of minimally invasive technique with only J mini-sternotomy and RDV on a conventional extracorporeal system; group 3 (control-MiECC): full sternotomy and type IV customized MiECC; and group 4 (control): full sternotomy on a conventional extracorporeal system. The MiAVR group had significantly less duration of x-clamp time ( 35.4 ± 11 minutes), postoperative respiratory support (4.1 ± 1 hour), postoperative hemorrhage (250 ± 50 mL), and intensive care unit stay (1 ± .5 days) than the control-conventional (group 4) group. Seventy-six percent of patients did not receive any blood products in MiAVR ( p = .025 vs. group 4). Incidence of atrial fibrillation (8%) and low cardiac output (14%) in MiAVR were significantly better than control. Critics of minimally invasive techniques sustain that potential advantages are offset by a longer cross-clamp and cardiopulmonary bypass duration, which may translate into inferior clinical outcomes. We advocate that our multidisciplinary approach supported by multiple technologies may be associated with faster recovery and superior outcomes than conventional minimally/conventional techniques.
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Günaydın et al. (2020) conducted a cohort in Aortic valve disease (n=200). Minimally invasive aortic valve replacement (MiAVR) on minimally invasive extracorporeal circulation (MiECC) vs. Full sternotomy on a conventional extracorporeal system was evaluated on Intensive care unit stay (days) (p=0.04). Minimally invasive aortic valve replacement on minimally invasive extracorporeal circulation significantly reduced intensive care unit stay, cross-clamp time, and postoperative hemorrhage compared to conventional full sternotomy.
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