Key result
Malnutrition linked to ~2.8-fold higher incident AF and increased one-year mortality in patients ≥75 years.
Why the study?
AF causes life-threatening thromboembolic complications in the elderly, creating a need to determine AF risk factors, evaluate the association of malnutrition markers with AF, and identify factors affecting mortality.
Is malnutrition associated with the development of atrial fibrillation and increased one-year mortality in individuals aged 75 years and older?
Cohort (n=358)
Is malnutrition associated with the development of atrial fibrillation and increased one-year mortality in individuals aged 75 years and older?
Effect estimate: 2.8-fold increase
p-value: p== 0.018
Malnutrition, as assessed by GLIM criteria, is associated with a 2.8-fold increased risk of developing atrial fibrillation and may increase one-year mortality in elderly patients.
May flag malnutrition for AF risk monitoring in adults ≥75; leaves open whether screening or intervention improves outcomes.
BACKGROUND: Atrial fibrillation (AF) is the most common rhythm disorder in the elderly. The AF can cause life-threatening thromboembolic complications. Therefore, there is a need to determine the risk factors of AF. In this study, we aimed to examine the association of markers of malnutrition with AF in individuals aged 75 years and older and to find the factors that may affect mortality. METHODS: In this prospective study, 358 consecutive individuals aged 75 years and older presenting to the cardiology outpatient clinic were included. All participants were divided into AF and sinus rhythm (SR) groups. In addition, a questionnaire and scoring system were used to assess malnutrition status. Information was obtained from all patients through outpatient clinic visits or telephone interviews for one year. Death from any cause was considered as the endpoint. RESULTS: = 0.018). GLIM malnutrition caused a 2.8-fold increase in the development of AF. CONCLUSIONS: Screening for malnutrition in the elderly is essential. According to GLIM criteria, malnutrition may play a role in the development of AF and increase one-year mortality in the elderly.
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Göçer et al. (2023) conducted a cohort in Atrial fibrillation (n=358). Malnutrition (GLIM criteria) vs. No malnutrition was evaluated on Death from any cause and development of atrial fibrillation (2.8-fold increase, p== 0.018). Malnutrition according to GLIM criteria was associated with a 2.8-fold increase in the development of atrial fibrillation and increased one-year mortality in individuals aged ≥75 years (P=0.018).
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