Key result
Achieving a 50% reduction in microalbuminuria in type 2 diabetic patients was associated with a significantly lower risk of renal or cardiovascular events (adjusted risk 0.41; 95% CI 0.15-0.96).
Why the study?
Does achieving a 50% reduction in microalbuminuria reduce the risk of renal or cardiovascular events in type 2 diabetic patients with microalbuminuria?
Population
216 type 2 diabetic patients with microalbuminuria
Comparison
Achieving a 50% reduction of microalbuminuria or… vs Patients without a 50% reduction of…
Design
Cohort
Follow-up
8 years
Authors
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Microalbuminuria reduction should not yet guide therapy in type 2 diabetes; leaves open whether targeting it improves renal or CV outcomes.
Observational (n=216)
Does achieving a 50% reduction in microalbuminuria reduce the risk of renal or cardiovascular events in type 2 diabetic patients with microalbuminuria?
Effect estimate: adjusted risk 0.41 (95% CI 0.15-0.96)
Absolute Event Rate: 12.9% vs 28.5%
Achieving a 50% reduction in microalbuminuria is associated with a significantly lower risk of subsequent renal and cardiovascular events in patients with type 2 diabetes.
Araki et al. (2007) conducted an observational in Type 2 diabetes with microalbuminuria (n=216). 50% reduction of microalbuminuria vs. No 50% reduction of microalbuminuria was evaluated on First occurrence of a renal or cardiovascular event (adjusted risk 0.41, 95% CI 0.15-0.96). Achieving a 50% reduction in microalbuminuria in type 2 diabetic patients was associated with a significantly lower risk of renal or cardiovascular events (adjusted risk 0.41; 95% CI 0.15-0.96).
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