April 23, 2025PLoS ONEOpen Access

Effects of repeated gravity changes during parabolic flight: Evidence of the need to assist space tourists to outer space

Q: What is the clinical evidence from this study?

Study design: Observational. Population: Healthy (n=17). Intervention: Parabolic flight vs. Low parasympathetic profile. Primary outcome: Psychological, physiological, and sensory responses.

Q: What does this research mean for the field?

Parabolic flight alters psychophysiological responses in novice flyers, with high baseline parasympathetic functioning predicting better initial adaptation but decreased interoceptive awareness during the critical recovery period. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

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Key result

High baseline parasympathetic function predicts better parabolic flight adaptation but decreased interoceptive awareness during recovery.

n=17

Why the study?

The impact of space travel and repeated gravity changes on unselected novice populations, as well as the role of baseline parasympathetic functioning in adaptation, remained unclear.

Does parabolic flight impact psychophysiological and sensory responses in healthy participants?

Comparison

High parasympathetic profile vs low parasympathetic profile

Design

Observational cohort study

Follow-up

1 week

Authors

BRBarbara Le RoyInserm CMCharles Martin‐KrummInserm VBVincent BeauchampsArmed Forces Institute of Pathology

Discussion

Member takes

Implication

May support recovery monitoring for space tourists; leaves open whether baseline parasympathetic activity predicts adaptation.

Study Design

Type

Observational (n=17)

Structured PICO

Does parabolic flight impact psychophysiological and sensory responses in healthy participants?

Population

17 healthy participants enrolled in the 79th ESA Parabolic Flight Campaign

Intervention

Parabolic flight experience (3-hour flight on board the Airbus A310)

Comparator

Baseline (day before the flight) and comparison between high parasympathetic (HP) and low parasympathetic (LP) profiles

Outcome

Psychophysiological and sensory responses and recovery one week latersurrogate

Parabolic flight induces psychophysiological and sensory changes, highlighting the need for postflight recovery monitoring and preparation for future space tourists.

Cite This Study

Roy et al. (2025) conducted an observational in Healthy (n=17). Parabolic flight vs. Low parasympathetic profile was evaluated on Psychological, physiological, and sensory responses. Parabolic flight altered psychophysiological responses, with high baseline parasympathetic functioning predicting better initial adaptation but decreased interoceptive awareness during recovery.

synapsesocial.com/papers/6a10fc3bd06b5b96589ff258 https://doi.org/10.1371/journal.pone.0320588

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Effects of repeated gravity changes during parabolic flight: Evidence of the need to assist space tourists to outer space

Discussion

Member takes

Implication

Study Design

Structured PICO

Cite This Study

Effects of repeated gravity changes during parabolic flight: Evidence of the need to assist space tourists to outer space

Discussion

Member takes

Implication

Study Design

Structured PICO

Cite This Study

Also Consider

Also Consider