Key result
The MATCH 3D CMR protocol yielded a significantly higher signal contrast ratio for intra-plaque hemorrhage compared to the conventional multi-contrast protocol (3.1 vs 0.4, p<0.001).
Why the study?
Does the MATCH 3D CMR technique improve carotid plaque characterization compared to conventional multi-contrast CMR in patients with carotid artery stenosis?
Population
4 healthy volunteers and 6 male patients (mean age 67) with ultrasonography-documented carotid artery stenosis
Comparison
Multi-contrast Atherosclerosis Characterization… vs Conventional multi-contrast CMR protocol
Design
Cohort, Blinded image review for composition identification
Authors
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May expedite efficient carotid plaque CMR; leaves open outcome trials before clinical adoption.
Observational (n=10)
No
Does the MATCH 3D CMR technique improve carotid plaque characterization compared to conventional multi-contrast CMR in patients with carotid artery stenosis?
Absolute Event Rate: 3.1% vs 0.4%
p-value: p=<0.001
The MATCH 3D CMR technique provides spatially co-registered multi-contrast images in a single 5-minute scan, demonstrating superior signal contrast for intra-plaque hemorrhage and calcification compared to conventional protocols.
Fan et al. (2014) conducted an observational in Carotid plaque (n=10). MATCH 3D CMR protocol vs. Conventional multi-contrast CMR protocol was evaluated on Signal contrast ratio for intra-plaque hemorrhage (IPH) with respect to the vessel wall (p=<0.001). The MATCH 3D CMR protocol yielded a significantly higher signal contrast ratio for intra-plaque hemorrhage compared to the conventional multi-contrast protocol (3.1 vs 0.4, p<0.001).
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