What question did this study set out to answer?

The aim is to determine if the catenoid shape of the interventricular septum contributes to idiopathic hypertrophic subaortic stenosis.

September 1, 1978CirculationOpen Access

Catenoid shape of the interventricular septum: possible cause of idiopathic hypertrophic subaortic stenosis.

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Why the study?

Is a catenoid shape of the interventricular septum associated with idiopathic hypertrophic subaortic stenosis (IHSS)?

Population

88 autopsied hearts

Design

Case-control

Authors

GHGrover M. HutchinsUniversity of Southern California BBBernadine H. BulkleyCardiac Imaging

Discussion

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Implication

May link catenoid septal geometry to IHSS; hypothesis-generating for mechanical role and requires larger validation.

Key Points

The aim is to determine if the catenoid shape of the interventricular septum contributes to idiopathic hypertrophic subaortic stenosis.
Studied hearts from eight autopsied patients with IHSS for septal curvature and thickness.
Compared findings with measurements from 80 other hearts without IHSS.
Analyzed septal shapes and fiber arrangements in relation to isometric contraction.
All eight IHSS hearts exhibited a catenoid septum shape, which was absent in the other 80 hearts.
The septum in IHSS hearts was concave to the left transversely and convex to the left apex-to-base.
The unique septal configuration correlated with muscle fiber disarray and localized hypertrophy due to isometric contraction.

Structured PICO

Is a catenoid shape of the interventricular septum associated with idiopathic hypertrophic subaortic stenosis (IHSS)?

Population

88 autopsied hearts (8 from patients with idiopathic hypertrophic subaortic stenosis [IHSS] and 80 other hearts)

Comparator

80 other hearts without IHSS

Outcome

Curvature and thickness of free walls and septumsurrogate

A catenoid configuration of the interventricular septum is uniquely present in IHSS and may mechanically explain the characteristic asymmetric septal hypertrophy and muscle fiber disarray.

Cite This Study

Hutchins et al. (1978) studied this question.

synapsesocial.com/papers/6a10fefc49545a83bbeed115 https://doi.org/10.1161/01.cir.58.3.392

Topics

Hypertrophic cardiomyopathy

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Catenoid shape of the interventricular septum: possible cause of idiopathic hypertrophic subaortic stenosis.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Catenoid shape of the interventricular septum: possible cause of idiopathic hypertrophic subaortic stenosis.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Topics

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