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October 1, 2021Journal of Zhejiang University SCIENCE BOpen Access

Current progress of computational modeling for guiding clinical atrial fibrillation ablation

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Key result

3D computational modeling offers a low-cost tool to predict AF ablation outcomes and identify personalized targets.

Why the study?

AF recurrence rates after catheter ablation remain high and outcomes vary significantly, leaving the optimal ablation strategy unsettled.

Can computational modeling guide and optimize personalized catheter ablation strategies for atrial fibrillation?

Design

Review

Authors

ZWZhenghong WuYLYunlong LiuLTLv Tong

Discussion

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Overview

May guide personalized AF ablation planning; leaves open need for prospective outcome validation before clinical use.

Structured PICO

Can computational modeling guide and optimize personalized catheter ablation strategies for atrial fibrillation?

P
Population
Patients with atrial fibrillation undergoing catheter ablation
I
Intervention
Three-dimensional computational modeling simulations for guiding ablation strategies

Computational modeling offers a repeatable, low-cost, and risk-free approach to predicting ablation outcomes and identifying personalized targets for atrial fibrillation.

Cite This Study

Wu et al. (2021) conducted a review in Atrial fibrillation. Computational modeling simulations of catheter ablation was evaluated. Three-dimensional computational modeling simulations of catheter ablation for atrial fibrillation offer a repeatable, low-cost tool for predicting outcomes and finding personalized ablation targets.

synapsesocial.com/papers/6a1109076f378c85fcf33261https://doi.org/10.1631/jzus.b2000727
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Atrial Fibrillation Ablation2017 · 32 citations
  2. 2Arrhythmia dynamics in computational models of the atria following virtual ablation of re-entrant drivers2018 · 25 citations
  3. 3Molecular Basis of Atrial Fibrillation Pathophysiology and Therapy2020 · 451 citations
  4. 4Electrophysiological significance of the interatrial conduction including cavo‐tricuspid isthmus during atrial fibrillation2020 · 23 citations
  5. 5Comparing Reentrant Drivers Predicted by Image-Based Computational Modeling and Mapped by Electrocardiographic Imaging in Persistent Atrial Fibrillation2018 · 46 citations