What question did this study set out to answer?

To develop a method for estimating normal tissue complication probabilities from non-uniform radiation dose distributions using dose-volume histograms.

November 1, 1985Radiation Research

Complication Probability as Assessed from Dose-Volume Histograms

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Authors

JLJohn LymanNational Institute of Genetics

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Implication

Methodological study demonstrates an algorithm estimating complication probability from dose-volume histograms, highlighting improved radiation treatment planning.

Key Points

To develop a method for estimating normal tissue complication probabilities from non-uniform radiation dose distributions using dose-volume histograms.
Designed a recursive algorithm utilizing established organ tolerance dose data for partial and full volume irradiation.
Applied the algorithm across arbitrary dose-volume histograms to model heterogeneous radiation delivery.
Established a computational model that derives complication probability from non-uniform dose distributions.
Provided a quantitative approach to assist radiation treatment planning and balance tumor control with normal tissue safety.

Cite This Study

John Lyman (1985) studied this question.

synapsesocial.com/papers/6a110a176da82ae745f33a06 https://doi.org/10.2307/3576626

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Implication

Methodological study demonstrates an algorithm estimating complication probability from dose-volume histograms, highlighting improved radiation treatment planning.

Complication Probability as Assessed from Dose-Volume Histograms

Discussion

Member takes

Implication

Key Points

Cite This Study

Complication Probability as Assessed from Dose-Volume Histograms

Discussion

Member takes

Implication

Key Points

Cite This Study

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