Answers are grounded in this paper and cite their sources.
The major penetrating membrane glycoprotein (band 3) was isolated from En(a-) and normal human erythrocytes. The two proteins differed only in carbohydrate composition. Band 3 from En(a-) erythrocytes contained greater amounts of galactose and N-acetyl-glucosamine. The loss of the sialoglycoprotein sialotetrasaccharides in the En(a-) cell is not compensated by the appearance of these units in band 3 of En(a-) erythrocytes.
No takes yet. Share an insight, caveat, or question.
Tanner et al. (1976) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: