Key result
A 36-month exercise program in women with ischemic heart disease improved aerobic capacity, blood pressure, and triglycerides at 4 months, with HDL cholesterol significantly increasing at 24 months.
Why the study?
Does a long-term exercise program improve aerobic capacity and coronary risk factors in women with ischemic heart disease?
Cohort (n=21)
Does a long-term exercise program improve aerobic capacity and coronary risk factors in women with ischemic heart disease?
Long-term exercise in women with ischemic heart disease yields most beneficial effects on aerobic capacity and risk factors within 4-8 months, with some further improvements up to 24 months.
Supports potential benefits of prolonged exercise in women with IHD; hypothesis-generating and should not change practice without RCTs.
We evaluated the time course of alteration in aerobic capacity and coronary risk factors associated with a 36-month exercise program in women with ischemic heart disease (IHD). Twenty-one patients participated in supervised exercise and home-based exercise programs for 36 months. However, of all patients, 11 patients completed the entire program. Oxygen uptake corresponding to lactate threshold (VO2LT), peak oxygen uptake (VO2peak), percent of body fat (%BF), systolic (BPs) and diastolic (BPd) blood pressure, total cholesterol (TC), low-density lipoprotein cholesterol (LDLC), high-density lipoprotein cholesterol (HDLC) and triglycerides (TG) were assessed before and 4, 8, 12, 24, and 36 months after exercise. The intensity of exercise was set at individually determined LT, i.e., 60 to 70% VO2peak. The daily amount of exercise during 36 months averaged 24.0 +/- 11.4 minutes per day. During the course of exercise program, VO2LT, VO2peak, BPs, BPd, and TG improved significantly at month 4. Although %BF decreased significantly at month 8 to 12, it tended to return to the initial level at month 36. On the other hand, a significant increase in HDLC was found at month 24 and improved state of HDLC remained unchanged thereafter. No changes were found in TC and LDLC. These results suggest that most of the beneficial effects of exercise on aerobic capacity and coronary risk factors in women with IHD are obtained within 4-8 months, with some further improvement seen with continued exercise up to 24 months.
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Takeda et al. (1996) conducted a cohort in Ischemic heart disease (n=21). Supervised and home-based exercise program was evaluated on Time course of alteration in aerobic capacity and coronary risk factors. A 36-month exercise program in women with ischemic heart disease improved aerobic capacity, blood pressure, and triglycerides at 4 months, with HDL cholesterol significantly increasing at 24 months.
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