Key result
Six months of aerobic exercise significantly increased HDL cholesterol and decreased total cholesterol and C-reactive protein compared to no activity in middle-aged obese women.
Why the study?
Does six months of aerobic exercise improve lipid profile and inflammatory markers in middle-aged obese women?
RCT (n=15)
Randomly divided
Does six months of aerobic exercise improve lipid profile and inflammatory markers in middle-aged obese women?
Absolute Event Rate: 46.1% vs 41.4%
p-value: p=<0.01
Six months of aerobic exercise significantly improves lipid profiles and reduces inflammatory markers in middle-aged obese women.
Supports aerobic exercise prescription in middle-aged obese women; confirms RCT benefits on lipids and CRP.
Background and objectives: The aim of this study was to investigate the effects of six months of aerobic exercise on lipid profile, inflammatory markers, and risk factors of cardiovascular disease in middle-aged obese women. Methods: Fifteen obese woman (age range: 35 to 45 years) with BMI of ≥30 Kg/m2 were enrolled via purposeful and convenience sampling. The participants were randomly divided into training (n=10) and control (n=5) groups. Blood samples (7 ml) were taken from all participants before the first training session and after the last training session. The women performed 60 minutes of aerobic exercise at 55-65% of heart rate reserve, three sessions a week, for six months. Data was analyzed using independent and paired t-tests and Mann-Whitney U and Wilcoxon tests at significance of 0.05. Results: After the six-month aerobic exercise, C-reactive protein, low-density lipoprotein, triglycerides, total cholesterol and high-density lipoprotein/total cholesterol decreased significantly. The exercise intervention also caused a significant increase in the concentrations of high-density lipoprotein and apolipoprotein A. Conclusion: Aerobic exercise can reduce the level of inflammatory markers associated with risk of cardiovascular disease and atherosclerosis.
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Moazami et al. (2018) conducted an RCT in Obesity (n=15). Aerobic exercise vs. No activity was evaluated on High-density lipoprotein cholesterol (HDL-C) at 6 months (mg/dl) (p=<0.01). Six months of aerobic exercise significantly increased HDL cholesterol and decreased total cholesterol and C-reactive protein compared to no activity in middle-aged obese women.
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