Metabolic syndrome was associated with higher depression scores (p=0.020), with elevated blood glucose in men (OR 1.697) and central obesity in women (OR 1.066) driving the association.
Cross-Sectional (n=416)
No
Is metabolic syndrome associated with self-perceived depression in adults?
Elevated plasma glucose in men and central obesity in women are associated with self-perceived depression, highlighting a co-occurrence that warrants clinical attention.
Effect estimate: OR 1.697 (men, glucose); OR 1.066 (women, waist)
p-value: p=0.020
OBJECTIVE: To study the association between metabolic syndrome (MetS) and self-perceived depression. DESIGN: A cross-sectional community-based study. SETTING: Semi-rural community of Lapinlahti in eastern Finland in 2005. SUBJECTS: A total of 416 subjects in eight adult birth cohorts (55%) with complete Beck Depression Inventory (BDI-21) questionnaire data. MAIN OUTCOME MEASURES: The values of the 21 BDI items and the BDI-21 total score with a cut-off point of 14/15 were used to study the association between MetS and depression. National Cholesterol Education Programme (NCEP) 2005 criteria were used for MetS classification. RESULTS: The total BDI-21 score was significantly higher in the subjects with MetS than in the subjects without MetS (p=0.020). Men with MetS were significantly worse off than men without MetS in the BDI-21 items of irritability (p=0.008), work inhibition (p=0.008), fatigability (p=0.037), weight loss (p=0.045), and loss of libido (p=0.014), while women were only so on the item of loss of libido (p=0.007). In a logistic regression analysis using a BDI-21 cut-off point of 14/15 adjusted for age, marital status, vocational education, and working status, significant association was retained between perceived depression and elevated blood glucose among men (OR=1.697) and large waist circumference among women (OR=1.066). CONCLUSION: Elevated plasma glucose in men and central obesity in women are associated with self-perceived depression. This co-occurrence deserves attention in clinical practice.
Miettola et al. (Tue,) conducted a cross-sectional in Metabolic syndrome and depression (n=416). Metabolic syndrome vs. Without metabolic syndrome was evaluated on BDI-21 total score and cut-off point of 14/15 (OR 1.697 (men, glucose); OR 1.066 (women, waist), p=0.020). Metabolic syndrome was associated with higher depression scores (p=0.020), with elevated blood glucose in men (OR 1.697) and central obesity in women (OR 1.066) driving the association.