Key result
Non-right precordial type 1 Brugada patterns may signal underlying Brugada syndrome and malignant ventricular arrhythmias.
Why the study?
Spontaneous isolated type 1 Brugada patterns confined to non-right precordial leads remain rarely described, particularly in individuals without a prior diagnosis of Brugada syndrome.
Case Report (n=1)
Recognizing Brugada patterns in non-right precordial leads is critical as they may indicate underlying Brugada syndrome and a high risk for malignant ventricular arrhythmias.
Answers are grounded in this paper and cite their sources.
Should not yet change Brugada screening practice; leaves open whether isolated non-right precordial patterns warrant expanded risk assessment.
Brugada syndrome is classically characterized by coved-type ST-segment elevation in leads V1 or V2. Repolarization abnormalities in peripheral leads have been previously reported in patients with Brugada syndrome; however, spontaneous isolated type 1 Brugada patterns confined to non-right precordial leads remain rarely described, particularly in individuals without a prior diagnosis of Brugada syndrome. TAKE-HOME MESSAGE: Spontaneous isolated type 1 Brugada patterns confined to non-right precordial leads may suggest underlying Brugada syndrome and serve as potential markers of malignant ventricular arrhythmias.
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Nam et al. (2026) conducted a case report in Brugada syndrome with atypical presentation (n=1). Spontaneous isolated type 1 Brugada pattern in non-right precordial leads was evaluated. Spontaneous isolated type 1 Brugada patterns confined to non-right precordial leads may suggest underlying Brugada syndrome and serve as potential markers of malignant ventricular arrhythmias.
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