Key result
General anaesthesia during paediatric cardiac catheterization is linked to ~178% higher complication odds versus sedation.
Why the study?
Paediatric cardiac catheterization in children with CHD requires anaesthetic techniques balancing procedural conditions with physiological risk, motivating an evaluation of associations between anaesthesia strategy and peri-procedural outcomes.
Does general anaesthesia compared to sedation increase the risk of complications in children with CHD undergoing catheterization procedures?
Cohort (n=307)
No
Does general anaesthesia compared to sedation increase the risk of complications in children with CHD undergoing catheterization procedures?
Effect estimate: aOR 2.78 (95% CI 1.12-6.91)
Absolute Event Rate: 20.6% vs 11.2%
p-value: p=0.024
General anaesthesia is associated with higher peri-procedural complication rates than sedation in children with CHD undergoing diagnostic catheterization.
Background: Paediatric cardiac catheterization in children with CHD requires anaesthetic techniques that balance procedural conditions with physiological risk. We evaluated anaesthesia management at a tertiary centre and examined associations between anaesthesia strategy and peri-procedural outcomes. Methods: This single-centre retrospective cohort included 307 catheterization procedures after exclusions. Anaesthesia was categorized as general anaesthesia or sedation. The primary outcome was any recorded complication. Results: Median age was 7.0 years (interquartile range 2.0–13.0), and 155/307 (50.5%) procedures were performed under general anaesthesia and 152/307 (49.5%) under sedation. Overall, 49/307 (16.0%) procedures were associated with at least one recorded complication; complications were more frequent with general anaesthesia than with sedation (20.6% versus 11.2%, p = 0.024). In diagnostic catheterization/angiography ( n = 175), general anaesthesia was independently associated with higher odds of any complication compared with sedation (adjusted odds ratio 2.78, 95% confidence interval 1.12–6.91; p = 0.028). Conclusions: In this cohort, general anaesthesia was associated with higher recorded complication rates than sedation, and this association persisted after adjustment within diagnostic catheterizations. Comparisons within interventional procedures were limited by sparse sedation data. These findings support procedure-specific, risk-adjusted evaluation when selecting anaesthesia strategy in the paediatric catheterization laboratory.
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Dalman et al. (2026) conducted a cohort in Congenital heart disease (CHD) (n=307). General anaesthesia vs. Sedation was evaluated on Any recorded complication (aOR 2.78, 95% CI 1.12-6.91, p=0.024). General anaesthesia during paediatric cardiac catheterization was associated with higher complication rates than sedation (20.6% vs 11.2%, p=0.024).
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