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December 17, 2019˜La œMedicina del lavoroOpen Access

Shift work was associated with significantly lower SDaNN values compared to fixed daytime work (50.80 ms vs 66.71 ms, p=0.014), suggesting altered cardiac autonomic modulation.

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Why the study?

Assessing the early impact of shift work-related circadian rhythm desynchronization and stress on cardiac autonomic modulation via heart rate variability in healthcare workers is an important occupational health objective.

Does shift work reduce heart rate variability in healthcare workers?

Population

42 healthcare workers (31 nurses and 11 physicians) aged 24-58 years of an Italian Hospital

Comparison

3-shift forward fast rotation vs fixed daytime shift

Design

Cross-sectional study

Key result

Shift work was associated with significantly lower SDaNN values compared to fixed daytime work (50.80 ms vs 66.71 ms, p=0.014), suggesting altered cardiac autonomic modulation.

Authors

LLLuigi Isaia LeccaDSDavide SetzuARAlberto Del Río

Discussion

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Overview

Shift work may signal early autonomic changes in healthcare workers; hypothesis-generating for CV risk and requires prospective validation.

Study Design

Type

Cross-Sectional (n=42)

Multicenter

No

Structured PICO

Does shift work reduce heart rate variability in healthcare workers?

P
Population
42 healthcare workers (31 nurses and 11 physicians) employed by an Italian Hospital, free from cardiovascular diseases, mean age 38.24 years, 71.4% female.
I
Intervention
Forward fast rotating shift work schedule (3 shifts: 7 am - 2 pm; 2 pm - 10 pm; 10 pm - 7 am).
C
Comparator
Fixed daytime shift work schedule (8 am - 2 pm).
O
Outcome
Heart Rate Variability (HRV) parameters including mean heart rate (HR), SDNN, SDaNN, and triangular index measured by short-term (60 minutes) Holter ECG.surrogate

Main Result

Absolute Event Rate: 50.8% vs 66.71%

p-value: p=0.014

Shift work in healthcare workers is associated with reduced short-term heart rate variability (SDaNN), suggesting early alterations in cardiac autonomic control.

Limitations

  • Cross-sectional study design does not allow inference about causality between shift work and decreasing HRV parameters
  • Small study population
  • Different prevalence rate of male and female subjects could have negatively influenced the results
  • Cross-sectional study design does not allow inference about causality between shift work and decreasing of HRV parameters
  • Different prevalence rate of male and female subjects

Cite This Study

Lecca et al. (2019) conducted a cross-sectional in Healthy health care workers (n=42). Shift work (forward fast rotating schedule) vs. Fixed daytime shift (8 am - 2 pm) was evaluated on Standard deviation of the average NN intervals in 5-minute segments (SDaNN) (p=0.014). Shift work was associated with significantly lower SDaNN values compared to fixed daytime work (50.80 ms vs 66.71 ms, p=0.014), suggesting altered cardiac autonomic modulation.

synapsesocial.com/papers/6a11be8e4bf0131c39178aachttps://doi.org/10.23749/mdl.v110i6.8048
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Shift work disrupts heart rate variability in shift workers2026
  2. 2Cardiac Autonomic Changes in Shift Workers as Assessed by Time-Domain Measures of Short-Term Heart Rate Variability2022
  3. 3Autonomic nervous system activity under rotational shift programs: effects of shift period and gender2021 · 4 citations
  4. 4Fluctuations in heart rate variability of health care workers during four consecutive extended work shifts and recovery during rest and sleep2017 · 25 citations
  5. 5Influence of shift work on sleep quality and circadian patterns of heart rate variability among nurses2024 · 10 citations