What question did this study set out to answer?

To evaluate nationwide incidence trends and overall survival patterns in patients diagnosed with chronic myelomonocytic leukemia.

November 23, 2016Leukemia & lymphoma/Leukemia and lymphoma

Incidence and survival outcomes of chronic myelomonocytic leukemia in the United States

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To evaluate nationwide incidence trends and overall survival patterns in patients diagnosed with chronic myelomonocytic leukemia.
Analyzed data from 2,238 patients diagnosed with chronic myelomonocytic leukemia (CMML) between 2003 and 2013 in the United States using the Surveillance, Epidemiology, and End Results (SEER) database.
Evaluated incidence across demographic groups and analyzed median overall survival stratified by age, sex, race, and diagnosis period (2003–2006 vs. 2007–2013).
CMML incidence rose significantly with advancing age and was notably lower among females, Black individuals, and Asian/Pacific Islander populations.
Median overall survival declined significantly as age increased: 25 months for ages 20–39, 20 months for 40–59, 18 months for 60–79, and 11 months for ages ≥80 (p < .01), with no significant differences by sex or race.
Median overall survival showed a modest improvement between diagnosis periods, rising from 14 months in 2003–2006 to 17 months in 2007–2013 (p < .01).

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Implication

Population-based cohort study reveals modest survival gains in chronic myelomonocytic leukemia alongside age-related declines, highlighting the need for novel therapies.

Cite This Study

Murthy et al. (2016) studied this question.

synapsesocial.com/papers/6a11c1331bf00cafc0178eda https://doi.org/10.1080/10428194.2016.1258700

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Implication

Population-based cohort study reveals modest survival gains in chronic myelomonocytic leukemia alongside age-related declines, highlighting the need for novel therapies.

Incidence and survival outcomes of chronic myelomonocytic leukemia in the United States

Key Points

Discussion

Implication

Cite This Study

Incidence and survival outcomes of chronic myelomonocytic leukemia in the United States

Key Points

Discussion

Implication

Cite This Study

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