Review details hematologic features and genetic drivers of myelodysplastic syndromes, highlighting mechanisms that govern progression to acute myeloid leukemia.
This review gives an account of the clinical and hematologic features of the myelodysplastic syndromes. It supplies the latest classification of these disorders, discusses the cytogenetic and molecular genetic changes that occur, and analyzes how some of these conditions convert to acute myeloid leukemia.
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Tefferi et al. (2009) studied this question.
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