Key result
Redo CABG off-pump compared to on-pump surgery was associated with lower rates of cardiovascular failure (20.3% vs 39.2%, p=0.043) and respiratory failure (2.7% vs 7.8%, p=0.047).
Why the study?
The study was conducted to compare the immediate results of treatment after redo coronary artery bypass grafting performed off pump versus with cardiopulmonary bypass.
Does redo coronary artery bypass grafting (reCABG) off pump reduce major adverse cardiovascular events and complications during hospitalisation compared to reCABG with cardiopulmonary bypass in patients with recurrence of angina pectoris?
Cohort (n=138)
No
Does redo coronary artery bypass grafting (reCABG) off pump reduce major adverse cardiovascular events and complications during hospitalisation compared to reCABG with cardiopulmonary bypass in patients with recurrence of angina pectoris?
In patients undergoing redo CABG, an off-pump approach was associated with a lower incidence of early postoperative complications compared to using cardiopulmonary bypass.
Aim. To compare the immediate results of treatment of patients after redo coronary artery bypass grafting (reCABG) off pump and with cardiopulmonary bypass.Methods. The retrospective study included 138 patients who underwent isolated reCABG for recurrence of angina pectoris in the period of 2013 to 2019 at the Almazov Research Centre. The operation was performed with cardiopulmonary bypass using isothermal blood cardioplegia in 74 cases (group A). Sixty-four operations were performed without cardiopulmonary bypass (group B). The primary endpoint was a major adverse cardiovascular event (e.g. myocardial infarction, acute cerebrovascular accident, cardiovascular death) during hospitalisation. Secondary endpoints were cardiovascular failure, respiratory failure, renal failure, and wound healing complications during hospitalisation.Results. Redo CABG with cardiopulmonary bypass compared with CABG off pump was more often complicated by cardiovascular failure (39.2% versus 20.3%, p = 0.043), respiratory failure (7.8% versus 2.7%, p = 0.047), and postpericardiotomy syndrome (13.5% versus 0%, p = 0.047). The revascularisation index was higher in the group of reCABG off pump (2.9) compared to the group of reCABG with cardiopulmonary bypass (2.4). In the early postoperative period there was a decrease in the duration of inpatient treatment and stay in the intensive care unit, the duration of surgery, as well as a lower incidence of postoperative complications in group B.Conclusion. Redo CABG showed satisfactory results in the early postoperative period. Performing reCABG off pump was advantageous and was associated with a decrease in the incidence of postoperative complications. Received 23 June 2020. Revised 9 September 2020. Accepted 10 September 2020. Funding: The study did not have sponsorship. Conflict of interest: Authors declare no conflict of interest. Author contributions Conception and design: I.K. Ismail-zade, V.K. GrebennikData collection and analysis: I.K. Ismail-zade, D.G. Zavarzina, N.R. AbutalimovaDrafting the article: I.K. Ismail-zade, I.Yu. Ivanov, G.I. IshmukhametovCritical revision of the article: V.K. Grebennik, M.l. GordeevFinal approval of the version to be published: M.L. Gordeev, V.K. Grebennik, I.K. Ismail-zade, G.I. Ishmukhametov, I.Yu. Ivanov, N.R. Abutalimova, D.G. Zavarzina
No takes yet. Share an insight, caveat, or question.
Гордеев et al. (2021) conducted a cohort in Recurrence of angina pectoris requiring redo CABG (n=138). Redo CABG off pump vs. Redo CABG with cardiopulmonary bypass was evaluated on Major adverse cardiovascular event (myocardial infarction, acute cerebrovascular accident, cardiovascular death) during hospitalisation. Redo CABG off-pump compared to on-pump surgery was associated with lower rates of cardiovascular failure (20.3% vs 39.2%, p=0.043) and respiratory failure (2.7% vs 7.8%, p=0.047).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: