Key result
Two to three distinct classes of trajectories were identified for postoperative symptoms, with age, longer ICU stay, and smoking associated with worse outcome trends over 3 months post-CABG.
Cohort (n=198)
Yes
Identifying symptom trajectories and associated risk factors post-CABG can help healthcare providers deliver targeted discharge planning and individualized care.
May support individualized post-CABG care; hypothesis-generating and requires prospective validation before practice change.
BACKGROUND: Coronary artery bypass grafting is one of the most common interventional revascularisation procedures used to treat coronary artery disease worldwide. With a wide variability in postoperative cardiac symptoms, identification of symptom trajectories during the 3-month postoperative recovery period may improve clinicians' abilities to support symptom recovery. AIMS: To identify distinct trajectories of cardiac symptoms seen over time in a cohort of patients during the 3-month post-coronary artery bypass grafting period, and determine clinical characteristics associated with different symptom trajectories postoperatively. METHODS: A prospective trial used the cardiac symptom survey to determine patient symptoms at baseline prior to surgery, and at 1 week, 6 weeks and 3 months following coronary artery bypass grafting. A latent class growth model and multivariate logistic regression analyses were used. RESULTS: Data were obtained from patients ( N=198) undergoing coronary artery bypass grafting in six medical centres of Taiwan, through patient medical records and interviews. Based on their frequency, trajectories were explored for the six most common postoperative symptoms including angina, dyspnoea, fatigue, depression, sleep problems and anxiety. We identified two to three distinct classes of trajectories for each symptom. Age, longer intensive care unit stay, fewer vessels bypassed, off-pump coronary artery bypass grafting, smoking history and lack of regular exercise were associated with worse symptom outcome trends over time. CONCLUSIONS: Using this unique trajectories-based research method, we are able to achieve a better understanding of symptom recovery patterns over time among coronary artery bypass grafting patients. Recognising risk factors and potential recovery patterns prior to surgery may allow healthcare providers to deliver targeted discharge planning and individualised care after coronary artery bypass grafting.
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Tsai et al. (2018) conducted a cohort in Coronary artery disease (n=198). Coronary artery bypass grafting was evaluated on Distinct trajectories of cardiac symptoms (angina, dyspnoea, fatigue, depression, sleep problems and anxiety). Two to three distinct classes of trajectories were identified for postoperative symptoms, with age, longer ICU stay, and smoking associated with worse outcome trends over 3 months post-CABG.
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